RNA生物农药作用机制及应用前景 Click here to download the full text Citation：王俊杰,彭伟杰,李戴敬,殷越,袁善奎,牛冬冬.RNA生物农药作用机制及应用前景.Journal of Plant Protection,2026,53(3):713-725 Hits: Download times: Author Name Affiliation E-mail Wang Junjie  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China College of Agriculture, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China    Peng Weijie  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China College of Agriculture, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China    Li Daijing  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China    Yin Yue  Institute for the Control of Agrochemicals, Ministry of Agriculture and Rural Affairs, Beijing 100125, China    Yuan Shankui  Institute for the Control of Agrochemicals, Ministry of Agriculture and Rural Affairs, Beijing 100125, China  skyuan76@sina.com  Niu Dongdong  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China  ddniu@njau.edu.cn  中文摘要:基于喷雾诱导基因沉默（spray-induced gene silencing,SIGS）技术的RNA生物农药是一种新兴的绿色防控手段，因其特异性强、环境友好等优势而备受关注。该文对RNA生物农药的作用机制、递送技术、应用场景及生态风险评价等进行系统综述，重点剖析SIGS技术发挥作用的主要途径，同时，深入分析RNA生物农药在作物保护中的应用潜力，并指出其在稳定性、环境适应性及生产成本等方面面临的挑战，特别强调了纳米载体与缓释制剂在提升RNA生物农药稳定性和生物活性方面的关键作用。此外，还探讨了制约RNA生物农药产业化进程的瓶颈问题，如田间试验数据匮乏、生态风险评估体系不健全及技术转化受阻等。未来，RNA生物农药的商业化需聚焦于提高递送效率、强化靶标精准度及保障长期生态安全，以期推动其在现代农业生产中的广泛应用。 中文关键词:RNA生物农药  基因沉默  递送系统  靶标设计  生态风险   Mechanisms and application prospects of RNA biopesticides Author Name Affiliation E-mail Wang Junjie  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China College of Agriculture, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China    Peng Weijie  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China College of Agriculture, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China    Li Daijing  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China    Yin Yue  Institute for the Control of Agrochemicals, Ministry of Agriculture and Rural Affairs, Beijing 100125, China    Yuan Shankui  Institute for the Control of Agrochemicals, Ministry of Agriculture and Rural Affairs, Beijing 100125, China  skyuan76@sina.com  Niu Dongdong  College of Plant Protection, Nanjing Agricultural University State Key Laboratory of Agricultural and Forestry Biosecurity, Nanjing 210095, Jiangsu Province, China  ddniu@njau.edu.cn  Abstract:RNA biopesticides based on spray-induced gene silencing(SIGS) represent a cutting-edge green pest management strategy, garnering significant attention owing to their high specificity and ecofriendliness. This paper systematically reviews the mechanisms of action, delivery technologies, application scenarios and ecological risk assessments of RNA biopesticides, focusing on the core pathways of SIGS technology. Furthermore, the potential of RNA biopesticides in crop protection is analyzed, highlighting existing challenges such as stability, environmental adaptability, and production costs. Notably, the role of nanocarriers and controlled-release formulations in enhancing the stability and biological activity of RNA biopesticides is emphasized. The bottlenecks in industrialization, including the paucity of field trial data, incomplete ecological risk assessment frameworks, and hurdles in technology transfer are discussed. Looking forward, the commercialization of RNA biopesticides must focus on improving delivery efficiency, enhancing target specificity, and ensuring long-term ecological safety to facilitate their widespread application in modern agriculture. keywords:RNA biopesticide  gene silencing  delivery systems  target design  ecological risk View Full Text  View/Add Comment  Download reader

Copyright:    京ICP备05006550号-2  You are the first  971344  Visitors
Head of Unit：Responsible Institution China Association for Scienc Organizers：China Society of Plant Protection and China Agricultural University Address：College of Agronomy and Biotechnology, China Agricultural University
Phone：86 (10) 62732528 E-mail：zbxb@cau.edu.cn
Technical Support：Tiller Beijing Science and Technology Development Co., Ltd.